Arthroscopy versus mini-arthrotomy approach for matrix-induced autologous chondrocyte implantation in the knee: a systematic review

Abstract Background Matrix-induced autologous chondrocyte implantation (mACI) can be performed in a full arthroscopic or mini-open fashion. A systematic review was conducted to investigate whether arthroscopy provides better surgical outcomes compared with the approach for mACI knee at midterm follow-up. Methods This following PRISMA guidelines. The literature search May 2021. All prospective studies reporting after chondral defects of were accessed. Only that clearly stated (arthroscopic mini-open) included. follow-up longer than 12 months eligible. Studies data from combined surgeries not eligible, nor those combining less committed cells (e.g., mesenchymal stem cells). Results Sixteen included, and 770 patients retrieved: 421 group, 349 mini-open. mean 44.3 (12–60) months. No difference between two groups found terms duration symptoms, age, body mass index (BMI), gender, defect size ( P > 0.1). Tegner Score = 0.3), Lysholm 0.2), International Knee Documentation Committee (IKDC) rate failures 0.2) revisions 0.06). Conclusion Arthroscopy mini-arthrotomy approaches achieve similar Level evidence II, studies.